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王鋼論文《中國中西醫結合腎病雜志》腎炎靈顆

來源:未知 作者:njboda 時間:2014-10-30 20:57

文獻出處:《中國中西醫結合腎病雜志》2002年5月第3卷第5期

腎炎靈顆粒劑治療難治性腎病綜合征的臨床研究

王 鋼 曾安平 孫 偉 孔 薇  顧佐寧 

萬晨旭  易 嵐  鄒燕勤

   目的: 評價腎炎靈顆粒劑治療難治性腎病綜合征的臨床療效及毒副反應。方法: 口服腎炎靈顆粒劑治療65 例難治性腎病綜合征患者4月~6月, 觀察患者癥狀、體征變化和血生化、尿蛋白等檢查結果以及與雷公藤多甙片副反應的對比。并對患者進行6 月~48 月的隨訪。結果: 腎炎靈顆粒劑對難治性腎病綜合征近期總有效率為78.46%, 對腎功能有保護作用, 隨訪復發率僅為15.4%, 其常見副反應明顯減少。結論: 腎炎靈顆粒劑對難治性腎病綜合征有較好的治療作用, 臨床副反應明顯低于雷公藤。

關鍵詞 腎炎靈顆粒劑  難治性腎病綜合征  中醫藥療法

Treatment of Refractory Nephrotic Syndrome byShenyan Ling Granule

WANG Gang, ZENG Anping, SUN Wei , et al

Nep h rology Center , Jiang su H ospi tal of T radi tional Chinese

Medi cine, Nanj ing (210029)

ABSTRACT  Objective:To investigate the efficacy and adverse effects of ShenYanLing Granule in treating refractory

nephrot ic sy ndrome (RNS) .Methods: 65 patients w ith RNS received 4~ 6 mo nths of oral shen yan Ling Gr anule. Clinical

symptoms and signs, blood and ur inary biochemical analysis, and the adverse effects of tripter ygium wilfordii hook were

investigated. Patieuts w ere followed up for 6~ 48 months. Results: The to tal remission rate of shenyan Ling Granule in

treating RNS w as 78. 4% during t he first course( 2 months) . ShenYanLing Gr anule protected renal function. T he recurrent

rate was only 15. 4% during the follow up. The usual adverse effect decreased significantly. Conclusion: ShenYanLing

Granule has a comprehensive effect and few er adverse effect than tr ipteryg ium w ilfordii hook in treatment of RNS.

KEY WORDS   ShenYanLing Granule  Refr actory Nephrotic Sy ndrome

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